abstract：:MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression of targeted mRNAs, which are important in the pathogenesis of autoimmune diseases. MiRNAs may have the potential to serve as biomarkers of disease. We evaluated serum levels of selected miRNAs and their associations with disease activity in juvenile ...

journal_title：Clinical rheumatology

authors： Kamiya Y,Kawada J,Kawano Y,Torii Y,Kawabe S,Iwata N,Ito Y

更新日期：2015-10-01 00:00:00

abstract：:The aims of our study are to observe the pregnancy outcome of anti-Sjögren's syndrome-related antigen A (SSA)/Ro-positive women and to predict the risk factors for adverse pregnancy outcome and neonatal lupus erythematosus (NLE). Clinical data of 126 anti-SSA/Ro-positive patients with 140 pregnancies were evaluated re...

journal_title：Clinical rheumatology

authors： Luo Y,Zhang L,Fei Y,Li Y,Hao D,Liu Y,Zhao Y

更新日期：2015-10-01 00:00:00

abstract：:Muscle pain and weakness in a rheumatoid arthritis (RA) patient has a broad differential, and myositis should be considered early in the disease course as serious limb and life-threatening sequelae may occur. A 55-year-old woman with a past medical history of methotrexate-controlled RA presented with right leg pain fo...

journal_title：Clinical rheumatology

authors： Jo D,Pompa T,Khalil A,Kong F,Wetz R,Goldstein M

更新日期：2015-10-01 00:00:00

abstract：:The study aims to comprehensively assess the profiles of myositis-specific autoantibodies (MSAs) in Chinese patients with polymyositis (PM)/dermatomyositis (DM) and compare them with a Japanese cohort. One hundred forty-five Chinese patients (68 classic DM, 25 clinically amyopathic DM [CADM], and 52 PM) and 165 Japane...

journal_title：Clinical rheumatology

authors： Chen Z,Hu W,Wang Y,Guo Z,Sun L,Kuwana M

更新日期：2015-09-01 00:00:00

abstract：:Paroxysmal crises of fever and systemic inflammation herald familial Mediterranean fever (FMF), considered as the archetype of all inherited systemic autoinflammatory diseases. Inflammatory bouts are characterized by short-term and self-limited abdominal, thoracic, and/or articular symptoms which subside spontaneously...

journal_title：Clinical rheumatology

authors： Rigante D,Lopalco G,Tarantino G,Compagnone A,Fastiggi M,Cantarini L

更新日期：2015-09-01 00:00:00

abstract：:Patients with osteoporosis often have chronic kidney disease (CKD). CKD is associated with bone and mineral disturbances, renal osteodystrophy, which like osteoporosis leads to a higher risk of fractures. Bisphosphonates are first-line therapy for osteoporosis; however, these are contra-indicated in patients with a GF...

journal_title：Clinical rheumatology

authors： Schipper LG,Fleuren HW,van den Bergh JP,Meinardi JR,Veldman BA,Kramers C

更新日期：2015-08-01 00:00:00

abstract：:With the growing awareness of the impact of chronic back pain and axial spondyloarthritis and recent breakthroughs in genetics and the development of novel treatments which may impact best on early disease, the need for markers that can facilitate early diagnosis and profiling those individuals at the highest risk for...

journal_title：Clinical rheumatology

authors： Reveille JD

更新日期：2015-06-01 00:00:00

abstract：:A variety of cardiovascular clinical manifestations have been described in patients with spondyloarthritis, especially in well-established ankylosing spondylitis. These include both structural heart disease, conduction defects and ischemic heart disease. The true prevalence of cardiovascular involvement in patients wi...

journal_title：Clinical rheumatology

authors： Gensler LS

更新日期：2015-06-01 00:00:00

abstract：:It is widely accepted that psychological variables are associated with self-reported pain and self-reported physical function in patients with musculoskeletal pain. However, the relationship between psychological variables and foot pain and foot function has not been evaluated in people with plantar heel pain. Eighty-...

journal_title：Clinical rheumatology

authors： Cotchett MP,Whittaker G,Erbas B

更新日期：2015-05-01 00:00:00

abstract：:The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and ...

journal_title：Clinical rheumatology

authors： Jones J,Wortmann R

更新日期：2015-05-01 00:00:00

abstract：:The use of biotechnology-derived medicines has significantly increased in recent decades. Although biosimilars undergo rigorous characterization as well as clinical studies to document their safety and effectiveness, they are highly complex molecules and small changes in the purification and production process of a bi...

journal_title：Clinical rheumatology

authors： Pineda C,Caballero-Uribe CV,de Oliveira MG,Lipszyc PS,Lopez JJ,Mataos Moreira MM,Azevedo VF

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study was to determine whether the prolactin -1149 G/T polymorphism confers susceptibility to systemic lupus erythematous (SLE) and rheumatoid arthritis (RA). A meta-analysis was conducted for examining the associations between prolactin -1149 G/T polymorphism and susceptibility to SLE or RA using alle...

journal_title：Clinical rheumatology

authors： Lee YH,Bae SC,Song GG

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study was to describe a single-center experience in the treatment and follow-up of cystoid macular edema patients. Clinical records of all patients with cystoid macular edema followed up in the Rheumatologic and Ophthalmological Unit of our center between 1993 and 2013 were retrospectively evaluated. T...

journal_title：Clinical rheumatology

authors： Taraborelli M,Cavazzana I,Fredi M,Airò P,Nascimbeni G,Tincani A,Franceschini F

更新日期：2015-04-01 00:00:00

abstract：:Our aim was to determine reasons for admission, the prevalence and spectrum of infections, and the outcomes in a multiethnic cohort of hospitalized systemic lupus erythematosus (SLE) patients in Durban, South Africa. We reviewed the records of hospitalized SLE patients seen over a 79-month period; the demographic data...

journal_title：Clinical rheumatology

authors： Dubula T,Mody GM

更新日期：2015-03-01 00:00:00

abstract：:Current Canadian osteoporosis guidelines recommend routine bone density screening of men at age 65. The purpose of this study is to determine the prevalence of osteoporosis in men aged 65-75 in after application of screening guidelines. All males aged 65-75 years who attended a large primary care clinic were advised o...

journal_title：Clinical rheumatology

authors： Ferrari R

更新日期：2015-03-01 00:00:00

abstract：:Haemorrhoidal disease (HD) is one of the most common diseases encountered by the clinicians of general surgery. Chronic constipation, pushing during defecation and increased abdominal pressure play an important role in development of haemorrhoidal disease. Patients with ankylosing spondylitis (AS) frequently use the V...

journal_title：Clinical rheumatology

authors： Caglayan M,Türkoğlu A,Oktayoglu P,Yıldız M,Dağlı AZ,Böyük A,Em S,Bozkurt M,Nas K

更新日期：2015-03-01 00:00:00

abstract：:This study aims to identify the clinical predictors of arthritis in patients with psoriasis and to evaluate the use of musculoskeletal ultrasonography (US) as a predictor for inflammatory structural progression in psoriatic patients. Measures of association (odds ratio (OR)) were tested, in a prospective, cohort 1-yea...

journal_title：Clinical rheumatology

authors： El Miedany Y,El Gaafary M,Youssef S,Ahmed I,Nasr A

更新日期：2015-02-01 00:00:00

abstract：:The objective of this study is to identify the clinical differences between infectious meningitis and neuropsychiatric systemic lupus erythematosus (NPSLE) in patients with SLE. Clinical manifestations, laboratory test results, and prognoses of 14 SLE patients complicated with various infectious meningitis, hospitaliz...

journal_title：Clinical rheumatology

authors： Chen J,Feng X,Wang H,Hua B,Ding C,Liu B,Sun L

更新日期：2015-02-01 00:00:00

abstract：:The purpose of this study is to evaluate the effects of targeting both the motivation and action phases of behaviour change in a 5-week intervention to increase physical activity (PA) among patients with rheumatoid arthritis (RA) not meeting current PA recommendations. In a randomised controlled trial, a control group...

journal_title：Clinical rheumatology

authors： Knittle K,De Gucht V,Hurkmans E,Peeters A,Ronday K,Maes S,Vlieland TV

更新日期：2015-02-01 00:00:00

abstract：:The vitamin D is involved in a wide variety of biological processes including bone metabolism, modulation of the immune response, and regulation of cell proliferation and differentiation. Vitamin D has several immunomodulatory effects through vitamin D receptor (VDR). A series of common single-nucleotide polymorphisms...

journal_title：Clinical rheumatology

authors： Zilahi E,Chen JQ,Papp G,Szántó A,Zeher M

更新日期：2015-02-01 00:00:00

abstract：:This study quantified the association between recreational physical activity and daily function in women with fibromyalgia, and determined if this association is mediated by symptoms of pain, depression, or body mass. Twenty-three women diagnosed with fibromyalgia participated in an observational survey study. Recreat...

journal_title：Clinical rheumatology

authors： Umeda M,Corbin LW,Maluf KS

更新日期：2015-01-01 00:00:00

abstract：:Autoinflammatory disorders (AIDs) are a novel class of diseases elicited by mutations in genes regulating the homeostasis of innate immune complexes, named inflammasomes, which lead to uncontrolled oversecretion of the proinflammatory cytokine interleukin-1β. Protean inflammatory symptoms are variably associated with ...

journal_title：Clinical rheumatology

authors： Cantarini L,Vitale A,Lucherini OM,De Clemente C,Caso F,Costa L,Emmi G,Silvestri E,Magnotti F,Maggio MC,Prinzi E,Lopalco G,Frediani B,Cimaz R,Galeazzi M,Rigante D

更新日期：2015-01-01 00:00:00

abstract：:Identification of patients with exposure to viral hepatitis is an important part of the care of patients with inflammatory arthritis. This study was conducted to assess the extent of hepatitis B and C screening, and the prevalence of viral hepatitis in a cohort of patients with established rheumatoid arthritis (RA). T...

journal_title：Clinical rheumatology

authors： Conway R,Doran MF,O'Shea FD,Crowley B,Cunnane G

更新日期：2014-12-01 00:00:00

abstract：:Joint hypermobility syndrome (JHS) is common in patients presenting to rheumatologists and can cause a range of symptoms leading to physical and psychological distress. Chronic musculoskeletal pain in patients with JHS often responds poorly to analgesics, and a pain management approach may be helpful. Since patients w...

journal_title：Clinical rheumatology

authors： Rahman A,Daniel C,Grahame R

更新日期：2014-11-01 00:00:00

abstract：:At the intersection of atopy and autoimmunity, we present a patient with seronegative rheumatoid arthritis (RA) who developed hypereosinophilia, without evidence of other etiologies, as she became rheumatoid factor (RF) positive. Although the magnitude of eosinophilia in patients with RA has been thought to reflect th...

journal_title：Clinical rheumatology

authors： Rosenstein RK,Panush RS,Kramer N,Rosenstein ED

更新日期：2014-11-01 00:00:00

abstract：:Transient receptor potential melastatin 7 (TRPM7) is involved in both normal physiological processes and pathology of various diseases. The purpose of this study was to explore the function and underlying mechanisms of TRPM7 channels in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) apoptosis induced by...

journal_title：Clinical rheumatology

authors： Li X,Wang X,Wang Y,Li X,Huang C,Li J

更新日期：2014-11-01 00:00:00

abstract：:Survival and outcomes have improved considerably among patients with juvenile dermatomyositis (JDM) in the west. However, mortality continues to be high in the developing world. There is paucity of literature on this aspect of JDM from developing countries. We reviewed case files of all patients with JDM registered in...

journal_title：Clinical rheumatology

authors： Singh S,Suri D,Aulakh R,Gupta A,Rawat A,Kumar RM

更新日期：2014-11-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is an inflammatory arthropathy, associated with skin and/or nail psoriasis and other possible systemic features. In the last years, PsA therapy has been revolutionized by the increasing knowledge in the pathogenetic mechanisms of the disease, involving dysfunction and oversecretion of multipl...

journal_title：Clinical rheumatology

authors： Costa L,Caso F,Cantarini L,Del Puente A,Scarpa R,Atteno M

更新日期：2014-09-01 00:00:00

abstract：:Distinction between infection and febrile disease flare in patients with systemic lupus erythematosus (SLE) is fundamental but often difficult to make, because clinical presentation can be similar. A systematic review of all articles indexed in PubMed through October 2013 was performed, in order to examine the potenti...

journal_title：Clinical rheumatology

authors： Serio I,Arnaud L,Mathian A,Hausfater P,Amoura Z

更新日期：2014-09-01 00:00:00

abstract：:Clinical characteristics of antitumor necrosis factor (TNF) agents-related tuberculosis (TB) in ankylosing spondylitis (AS) are not well described. The aim was to compare the incidences and the characteristics of TB in AS and rheumatoid arthritis (RA) during TNF inhibitor treatment. AS (n = 1,322) and RA (n = 3,154) p...

journal_title：Clinical rheumatology

authors： Kim HW,Park JK,Yang JA,Yoon YI,Lee EY,Song YW,Kim HR,Lee EB

更新日期：2014-09-01 00:00:00

abstract：:Recently, the Ankylosing Spondylitis Disease Activity Score (ASDAS), a new index, has been shown to be validated and highly discriminatory in assessing ankylosing spondylitis (AS) disease activity. This study is to evaluate the performance of ASDAS in a local Chinese cohort of AS in a cross-sectional setting and to co...

journal_title：Clinical rheumatology

authors： Au YL,Wong WS,Mok MY,Chung HY,Chan E,Lau CS

更新日期：2014-08-01 00:00:00

abstract：:Innate immunity has been widely accepted as one of the major cause for the alteration of immune system and progression of autoimmune diseases. Natural killer (NK) cells and natural killer T (NKT) cells have not been explored in clinical studies for their cytolytic components in association with rheumatoid arthritis (R...

journal_title：Clinical rheumatology

authors： Aggarwal A,Sharma A,Bhatnagar A

更新日期：2014-08-01 00:00:00

abstract：:Disability is a common problem in patients with gout. Recently, the Health Assessment Questionnaire Disability Index (HAQ-DI) was recommended for assessing patient reported activity limitations in gout. However, few studies have explored experiences and issues of disability from the perspective of gout patients themse...

journal_title：Clinical rheumatology

authors： ten Klooster PM,Vonkeman HE,Voshaar MA,Bode C,van de Laar MA

更新日期：2014-08-01 00:00:00

abstract：:The aim of the study was to determine the prevalence and factors associated with bursitis/tendonitis disorders in Puerto Ricans with diabetes mellitus (DM). A cross-sectional study was performed in 202 adult Puerto Ricans (100 DM patients and 102 non-diabetic subjects). For each participant, a complete medical history...

journal_title：Clinical rheumatology

authors： Font YM,Castro-Santana LE,Nieves-Plaza M,Maldonado M,Mayor AM,Vilá LM

更新日期：2014-07-01 00:00:00

abstract：:Paediatric systemic lupus erythematosus (pSLE) refers to childhood-onset systemic lupus erythematosus. pSLE has its own unique characteristics, and its pathogenesis is unclear. To study the relationship between microRNAs (miRNAs) and pSLE, we selected three pSLE patients who were newly diagnosed and had not yet been t...

journal_title：Clinical rheumatology

authors： Zhu J,Huang X,Su G,Wang L,Wu F,Zhang T,Song G

更新日期：2014-06-01 00:00:00

abstract：:This study aimed to determine the frequency of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibodies in a cohort of patients with palindromic rheumatism (PR) and to find determinants for progression to rheumatoid arthritis (RA). All new cases of PR (n=90) were included prospectively and followed up ...

journal_title：Clinical rheumatology

authors： Emad Y,Anbar A,Abo-Elyoun I,El-Shaarawy N,Al-Hanafi H,Darwish H,Gamil M,Rasker JJ

更新日期：2014-06-01 00:00:00

abstract：:The objective is to investigate the accrual rate and risk factors of chronic kidney disease (CKD) in an inception cohort of patients with systemic lupus erythematosus (SLE) followed at a single tertiary center. A prospectively collected database of 256 consecutive patients with SLE followed over a 25-year period was s...

journal_title：Clinical rheumatology

authors： Pokroy-Shapira E,Gelernter I,Molad Y

更新日期：2014-05-01 00:00:00

abstract：:The objective of the study was to study the functioning and health-related quality of life (HRQoL) in patients with systemic sclerosis (SSc) and its associated factors. Consecutive SSc patients and an equal number of age- and gender-matched healthy controls were recruited for the assessment of functioning and HRQoL by...

journal_title：Clinical rheumatology

authors： Chan PT,Mok CC,Chan KL,Ho LY

更新日期：2014-05-01 00:00:00

abstract：:The aim of the study was to assess mean platelet volume (MPV) in children with systemic lupus erythematosus (SLE) at the active and inactive stages. Twenty children with SLE and 30 age- and gender-matched controls were enrolled. Demographic data, SLE disease activity index (SLEDAI), erythrocyte sedimentation rate (ESR...

journal_title：Clinical rheumatology

authors： Yavuz S,Ece A

更新日期：2014-05-01 00:00:00

abstract：:Azathioprine (AZA) is indicated for the treatment of systemic lupus erythematosus (SLE). Thiopurine methyltransferase (TPMT) is the rate-limiting enzyme in the steps of AZA metabolization. Heritable deficiency of TPMT enzyme activity and polymorphisms may lead to leukopenia. This study aims to detect TPMT polymorphism...

journal_title：Clinical rheumatology

authors： Chen D,Lian F,Yuan S,Wang Y,Zhan Z,Ye Y,Qiu Q,Xu H,Liang L,Yang X

更新日期：2014-04-01 00:00:00